The results of research studies utilizing Orthofix products and technologies have been published in a variety of forums, including scholarly journals. Some of these works are highlighted below under their respective therapeutic area.
Bone Growth Therapies
With almost 40 years of healing patients, our bone growth therapy devices are the number one prescribed bone growth stimulators in the U.S. These devices provide patients with safe, non-surgical treatment options for promoting spinal fusion and healing nonunion fractures. Using Orthofix’s pulsed electromagnetic field (PEMF) technology, the devices generate a uniform, low-level electrical field that helps activate and augment the body’s natural healing process to enhance bone fusion.
Randomized, prospective, and controlled clinical trial of pulsed electromagnetic field stimulation for cervical fusion
A randomized double-blind prospective study of the efficacy of pulsed electromagnetic fields for interbody lumbar fusions
Pulsed electromagnetic field stimulation may improve fusion rates in cervical arthrodesis in high-risk populations
Pulsed electromagnetic fields for the treatment of tibial delayed unions and nonunions. A prospective clinical study and review of the literature
Spine fusion for discogenic low back pain: outcomes in patients treated with or without pulsed electromagnetic field stimulation
Three-and 4-level lumbar arthrodesis using adjunctive pulsed electromagnetic field stimulation: a multicenter retrospective evaluation of fusion rates and a review of the literature
Our M6™ artificial discs are the natural choice for helping preserve motion in patients undergoing cervical or lumbar disc replacement. Designed to mimic a patient’s natural vertebral disc, our M6 discs are the only artificial discs that incorporate an artificial nucleus and woven fiber annulus. This design aims to provide the same motion characteristics of a natural disc, including compressive capabilities and a controlled range of motion.
Longitudinal assessment of segmental motion of the cervical spine following total disc arthroplasty: a comparative analysis of devices
Comparison of M6-C and Mobi-C cervical total disc replacement for cervical degenerative disc disease in adults
Cervical total disc replacement using a novel compressible prosthesis: Results from a prospective Food and Drug Administration-regulated feasibility study with 24-month follow-up
Are Collapsed Cervical Discs Amenable to Total Disc Arthroplasty?: Analysis of Prospective Clinical Data With 2-Year Follow Up
Comparative Study Between M6-C and Mobi-C Cervical Artificial Disc Replacement: Biomechanical Outcomes and Comparison with Normative Data
Prospective, multicenter clinical trial comparing M6-C compressible six degrees of freedom cervical disc with anterior cervical discectomy and fusion for the treatment of single-level degenerative cervical radiculopathy: 2-year results of an FDA investigational device exemption study
Our biologic solutions play an important role in a number of surgical applications, including allografts with viable cells, structural allografts, synthetic bone grafts, and amniotic membranes. By supplying the key elements needed for bone healing coupled with its enhanced handling properties, the Trinity ELITE® and Trinity Evolution™ allografts with viable cells have been implanted in more than 200,000 procedures.
Commercial Bone Grafts Claimed as an Alternative to Autografts: Current Trends for Clinical Applications in Orthopaedics
Bone Graft Options in Spinal Fusion: A Review of Current Options and the Use of Mesenchymal Cellular Bone Matrices
Investigating the efficacy of allograft cellular bone matrix for spinal fusion: a systematic review of the literature
A large database study of hospitalization charges and follow-up re-admissions in US lumbar fusion surgeries using a cellular bone allograft (CBA) versus recombinant human bone morphogenetic protein-2 (rhBMP-2)
Cost-Effectiveness of Peptide Enhanced Bone Graft i-Factor versus Use of Local Autologous Bone in Anterior Cervical Discectomy and Fusion Surgery
Efficacy, Cost, and Complications of Demineralized Bone Matrix in Instrumented Lumbar Fusion: Comparison With rhBMP-2
Posterolateral lumbar spine fusion using a novel demineralized bone matrix: a controlled case pilot study
Comparison of cortical ring allograft and plate fixation with autologous iliac bone graft for anterior cervical discectomy and fusion
Efficacy of demineralized bone matrix paste for maxillary sinus augmentation: A histologic and clinical study in humans
Comparative Efficacy of 2 Different Demineralized Bone Matrix Allografts in Treating Long-Bone Nonunions in Heavy Tobacco Smokers
We are committed to helping restore quality of life for our patients through advanced interbody and fixation solutions that aid surgeons in repairing spinal alignment, improving disc height, providing nerve decompression and correcting instabilities. Our spine fixation products are used globally in a variety of spine procedures involving deformity correction, minimally invasive approaches, sacroiliac joints, degenerative disc disease, trauma and tumors.
The use of anterior subcutaneous internal fixation (INFIX) for treatment of pelvic ring injuries in major trauma patients, complications and outcomes
Orthofix offers innovative and minimally invasive orthopedics solutions to help surgeons improve their patient’s quality of life. Designed to address the lifelong bone and joint health needs of patients of all ages, our orthopedics products help patients achieve a more active and mobile lifestyle when compared to other surgical solutions. Our well-rounded product lines offer comprehensive solutions for pediatrics, limb reconstruction, trauma, and foot & ankle specialties.