IsoTis Biologics
IsoTis biologics are engineered to facilitate bony fusion for spine, orthopedics, and other surgical applications. Our comprehensive portfolio of industry-leading bone grafts includes premium fiber and putty demineralized bone matrices (DBMs), advanced bioactive synthetics, and procedural solutions for streamlined PCFs, PLFs, and open and MIS TLIFs and PLIFs.
Developed by dedicated research and development teams at our in-house tissue bank in Irvine, CA, our products reflect a commitment to innovation, quality, and patient care. With validation from rigorous peer-reviewed research studies, IsoTis biologics demonstrate robust bone growth and successful clinical outcomes through their osteoconductive, osteoinductive, and/or osteogenic properties.
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DBM Fibers
IsoTisDBM fibers provide an osteoconductive scaffold with osteoinductive potential, combining fiber-based architecture with versatile handling characteristics to support bone formation. Strand™ Plus incorporates proprietary Accell™ technology, a proprietary form of DBM processed to create a porous high-surface area structure, allowing earlier access to the naturally occurring growth factors1, while the portfolio offers a range of configurations designed to meet different surgical and handling needs.
DBM Putties
IsoTis DBM putties combine demineralized bone matrix with a selection of high-quality carriers to provide moldable, easy-to-handle graft solutions. Accell™ Evo3 and Accell Connexus incorporate Accell technology, a proprietary form of DBM processed to create a porous high-surface area structure, allowing earlier access to the naturally occurring growth factors1, and a variety of handling characteristics to accommodate surgeon preference and procedural needs.
Synthetics
IsoTis synthetic bone grafts provide osteoconductive scaffolds designed to support new bone formation, with both traditional and advanced graft technologies available. The portfolio combines versatile formats with exceptional handling characteristics and graft integrity to address a range of bone grafting applications.
Procedural Solutions
Procedural solutions pair specialized graft materials with targeted delivery systems to help streamline graft placement in specific surgical applications. These solutions are designed to support efficient, controlled delivery while addressing procedure-specific needs.
Traditional Allografts
Traditional allografts provide human bone tissue in a variety of forms and configurations to support bone grafting needs. These solutions offer structural and osteoconductive options for use across a broad range of surgical applications.
References
- Khaliq S, Lollis R, Bell D, Oliver R, Walsh WR, and Ingram R, Evaluation of a Next Generation DBM Putty in a Posterlateral Spinal Fusion Model, (2009)Integra LifeSciences Corporation.
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Connect with a member of our team to learn more about our biologics portfolio and find the right solution for your fusion needs.